The FX comes standard with seat-mounted side airbags for the front passengers and side curtain airbags for both rows. Active head restraints are standard for both rows; most of today's vehicles with active head restraints just have them up front. These devices help prevent whiplash in rear collisions. Like most crossovers, the FX has four-wheel-disc antilock brakes, an electronic stability system, traction control and a tire pressure monitoring system.

At this time, neither the National Highway Traffic Safety Administration nor the Insurance Institute for Highway Safety has fully crash tested the FX. IIHS did complete a frontal crash test of the FX, and it earned the top score of Good.